Semnan University Press Applied Chemistry Today 2981-2437 14 52 2019 09 23 Determination of mangiferin using carbon paste electrode modified with ionic liquid and NiFe2O4 nanoparticles Determination of mangiferin using carbon paste electrode modified with ionic liquid and NiFe2O4 nanoparticles 63 76 3741 10.22075/chem.2019.15220.1473 FA Hadi Beitollahi Environment Department, Institute of Science and High Technology and Environmental Sciences, Graduate University of Advanced Technology, Kerman, Iran Shohreh Jahani NanoBioElectrochemistry Research Center, Bam University of Medical Sciences, Bam, Iran Journal Article 2018 08 11 A highly sensitive electrochemical sensor was fabricated based on ionic liquid and NiFe2O4 nanoparticles modified carbon paste electrode for determination of mangiferin. The modified electrode exhibited excellent electrocatalytic activity towards the oxidations mangiferin in phosphate buffer solution (pH 7.0). Cyclic voltammetry (CV), chronoamperometry (CHA) and differential pulse voltammetry (DPV) were used to investigate the electrochemical reaction of mangiferin at the modified electrode. It dramatically enhanced mangiferin oxidation current and shifted its potential towards less positive potential when compared to bare CPE. The peak current vs. mangiferin concentration diagram was found to be linear in range of 0.1 to 500.0 μM with the respective slope of 0.0576 μA μM-1. The detection limit obtained by DPV was 0.09 μM (S/N = 3). The proposed sensor was proved to be applicable for the determination of the mangiferin in urine samples. A highly sensitive electrochemical sensor was fabricated based on ionic liquid and NiFe2O4 nanoparticles modified carbon paste electrode for determination of mangiferin. The modified electrode exhibited excellent electrocatalytic activity towards the oxidations mangiferin in phosphate buffer solution (pH 7.0). Cyclic voltammetry (CV), chronoamperometry (CHA) and differential pulse voltammetry (DPV) were used to investigate the electrochemical reaction of mangiferin at the modified electrode. It dramatically enhanced mangiferin oxidation current and shifted its potential towards less positive potential when compared to bare CPE. The peak current vs. mangiferin concentration diagram was found to be linear in range of 0.1 to 500.0 μM with the respective slope of 0.0576 μA μM-1. The detection limit obtained by DPV was 0.09 μM (S/N = 3). The proposed sensor was proved to be applicable for the determination of the mangiferin in urine samples. https://chemistry.semnan.ac.ir/article_3741_b939c292d8e3661fe350ece73532806e.pdf