Semnan University Press Applied Chemistry Today 2981-2437 10 37 2016 02 20 Salicylic acid as a naturally green Brønsted acid catalyst for eco-friendly and simple synthesis of polysubstituted dihydro-2-oxypyrroles under ambient temperature Salicylic acid as a naturally green Brønsted acid catalyst for eco-friendly and simple synthesis of polysubstituted dihydro-2-oxypyrroles under ambient temperature 79 86 724 10.22075/chem.2017.724 FA Farzaneh Mohamadpour Mojtaba Lashkari Malek Taher Maghsoodlou Reza Heydari Journal Article 2017 01 15 An efficient and environmental friendly methodology for the synthesis of polysubstituted dihydro-2-oxypyrroles via a one-pot four-component domino condensation of dialkyl acetylenedicarboxylate, formaldehyde and amines (aromatic and aliphatic) at present of    salicylic acid as an economical and naturally green Brønsted acid catalyst under ambient temperature with excellent yields and short reaction times is described. Green, natural, inexpensive and non-toxic catalyst, easily separated with no column chromatographic separation and highly efficient is an option for the simple synthesis of these rings. An efficient and environmental friendly methodology for the synthesis of polysubstituted dihydro-2-oxypyrroles via a one-pot four-component domino condensation of dialkyl acetylenedicarboxylate, formaldehyde and amines (aromatic and aliphatic) at present of    salicylic acid as an economical and naturally green Brønsted acid catalyst under ambient temperature with excellent yields and short reaction times is described. Green, natural, inexpensive and non-toxic catalyst, easily separated with no column chromatographic separation and highly efficient is an option for the simple synthesis of these rings. https://chemistry.semnan.ac.ir/article_724_a5057417817c7f542e7fd5151804113a.pdf