Semnan University Press Applied Chemistry Today 2981-2437 11 39 2016 06 21 Microwave-assisted, a fast and efficient method for the synthesis of 1, 5-benzodiazepine derivatives by Nanomagnetic-supported sulfonic acid under solvent free condition Microwave-assisted, a fast and efficient method for the synthesis of 1, 5-benzodiazepine derivatives by Nanomagnetic-supported sulfonic acid under solvent free condition 187 196 750 10.22075/chem.2017.750 FA Journal Article 2017 01 15 In this paper, magnetic nanoparticles functionalized with sulfonic acid group as a heterogeneous and recyclable catalyst for the rapid synthesis of 1,5-benzodiazepine derivatives from condensation reaction of 2-phenylenediamine with various Chalcones under microwave irradiation and solvent-free conditions was used. The nano magnetic supported sulfonic acid provides high reactivity and, also it is separated easily from the reaction mixture by using an external magnet. The use of microwaves in solvent free condition compared to conventional heating methods, rapid, simple, safety, high yields and purity of the products of the remarkable advantages of this method is considered. In this paper, magnetic nanoparticles functionalized with sulfonic acid group as a heterogeneous and recyclable catalyst for the rapid synthesis of 1,5-benzodiazepine derivatives from condensation reaction of 2-phenylenediamine with various Chalcones under microwave irradiation and solvent-free conditions was used. The nano magnetic supported sulfonic acid provides high reactivity and, also it is separated easily from the reaction mixture by using an external magnet. The use of microwaves in solvent free condition compared to conventional heating methods, rapid, simple, safety, high yields and purity of the products of the remarkable advantages of this method is considered. https://chemistry.semnan.ac.ir/article_750_142dc342b9d0aa46b9ff8923107d5df0.pdf