Synthesis, characterization and antibacterial activity of new heteroleptic complexes of Ni(II) and Pt(II) complexes with 5-bromo-2-hydroxybenzaldehyde-4-phenylthiosemicarbazone in presence of imidazole and triphenylphosphine as axiuliary ligands

Document Type : Original Article

Authors

1 Department of Chemistry, Payame Noor University (PNU), 19395-4697 Tehran, Iran

2 گروه شیمی، دانشکده علوم، دانشگاه شهید چمران اهواز، اهواز، ایران

Abstract

Abstract In this research work new heteroleptic Ni(II) and Pt(II) complexes have been synthesized by using 5-bromo-2-hydroxybenzaldehyde-4-phenylthiosemicarbazone as main ligand and triphenylphosphine and imidazole as auxiliary ligands. The ligand and complexes have been characterized by elemental analysis and spectroscopy. On the basis of results thiosemicarbazone is coordinated to metal ion as a dianionic tridentate ONS ligand and the coordination sphere is completed by the auxiliary ligand. Antibacterial activity of ligand and complexes was evaluated against B. subtilis and S. aureus and P. aeruginosa All complexes exhibit more inhibitory effect than the parent ligand and complexes containing imidazole have more activity than others.

Keywords

Main Subjects

References

[1] M.d.S. de P. Silva, I.C.N. Diógenes, I.M.M. de Carvalho, K.P.S. Zanoni, R.C. Amaral, N.Y.M. Iha, J. Photochem. Photobio. A, 314 (2016) 75.
[2] A. Bharti, P. Bharati, U.K. Chaudhari, A. Singh, S.K. Kushawaha, N.K. Singh, M.K. Bharty, Polyhedron, 85 (2015) 712.
[3] A. Barve, A. Kumbhar, M. Bhat, B. Joshi, R. Butcher, U. Sonawane, R. Joshi, Inorg. Chem., 48 (2009) 9120.
[4] J. Ravichandran, P. Gurumoorthy, M.I. Musthafa, A.K. Rahiman, Spectrochim. Acta Part A, 133 (2014) 785.
[5] A.M. Mansour, J. Coord. Chem., 67 (2014) 2680.
[6] P. Zhao, Q. Wei, J. Dong, F. Ding, J. Li, L. Li, J. Coord. Chem., 69 (2016) 2437.
[7] R. Patel, S. Rawat, M. Choudhary, V.P. Sondhiya, D.K. Patel, K. Shukla, D.K. Patel, Y. Singh, R. Pandey, Inorg. Chim. Acta, 392 (2012) 283.
[8] S. Regupathy, M.S. Nair, Spectrochim. Acta Part A, 75 (2010) 656.
[9] P.G. Cozzi, Chem. Soc. Rev., 33 (2004) 410.
[10] J. Casas, M. Garcıa-Tasende, J. Sordo, Coord. Chem. Rev., 209 (2000) 197.
[11] T.S. Lobana, R. Sharma, G. Bawa, S. Khanna, Coord. Chem. Rev., 253 (2009) 977.
[12] Y. Yu, D.S. Kalinowski, Z. Kovacevic, A.R. Siafakas, P.J. Jansson, C. Stefani, D.B. Lovejoy, P.C. Sharpe, P.V. Bernhardt, D.R. Richardson, J. Med. Chem., 52 (2009) 5271.
[13] M. Khandani, T. Sedaghat, N. Erfani, M.R. Haghshenas, H.R. Khavasi, J. Mol. Struct., 1037 (2013) 136.
[14] T. Sedaghat, A. Golalzadeh, H. Motamedi, Phosphorus, Sulfur, and Silicon and the Related Elements, 188 (2013) 1694.
[15] L. Latheef, E. Manoj, M.P. Kurup, Polyhedron, 26 (2007) 4107.
[16] V. Suni, M.P. Kurup, M. Nethaji, Spectrochim. Acta Part A, 63 (2006) 174.
[17] J.G. Da Silva, A.A. Recio Despaigne, S.R.W. Louro, C.C. Bandeira, E.M. Souza-Fagundes, H. Beraldo, Eur. J. Med. Chem., 65 (2013) 415.
[18] A.I. Matesanz, P. Albacete, P. Souza, Polyhedron, 109 (2016) 161.
[19] S. Chandra, Vandana, Spectrochim. Acta Part A, 129 (2014) 333.
[20] E. Viñuelas-Zahínos, F. Luna-Giles, P. Torres-García, M.C. Fernández-Calderón, Eur. J. Med. Chem., 46 (2011) 150.
[21] T. Sedaghat, R. Habibi, H. Motamedi, H.R. Khavasi, Chin. Chem. Lett., 23 (2012) 1355.
[22] R. Amin, B. Krammer, N. Abdel-Kader, T. Verwanger, A. El-Ansary, Eur. J. Med. Chem., 45 (2010) 372.
[23] V. Vrdoljak, I. Đilović, M. Rubčić, S.K. Pavelić, M. Kralj, D. Matković–Čalogović, I. Piantanida, P. Novak, A. Rožman, M. Cindrić, Eur.J. Med. Chem., 45 (2010) 38.
[24] P. Novak, K. Pičuljan, T. Hrenar, T. Biljan, Z. Meić, J. Mol. Struct., 919 (2009) 66.
[25] V. Vrdoljak, M. Cindrić, D. Matković‐C̆alogović, B. Prugovecki, P. Novak, B. Kamenar, Z. Anorg. Allg. Chem., 631 (2005) 928.
[26] Saswati, R. Dinda, C.S. Schmiesing, E. Sinn, Y.P. Patil, M. Nethaji, H. Stoeckli-Evans, R. Acharyya, Polyhedron, 50 (2013) 354.
[27] I. Đilović, M. Rubčić, V. Vrdoljak, S.K. Pavelić, M. Kralj, I. Piantanida, M. Cindrić, Bioorg. Med. Chem. , 16 (2008) 5189.
[28] B. Tweedy, Phytopathology, 55 (1964) 910.
[29] Y. Anjaneyulu, R.P. Rao, Synth.React.Inorg.Met.-Org. Chem., 16 (1986) 257.
[30] M.S. Refat, F.A. Al-Saif, J. Therm. Anal. Calorim., 120 (2015) 863.
[31] P.P. Netalkar, S.P. Netalkar, V.K. Revankar, Polyhedron, 100 (2015) 215.
[32] R. Juan-Luis, F. Alian, Pseudomonas, Virulence and gene regulation, Springer, 2007.
[33] D.M. Livermore, Clin. Infect. Dis., 34 (2002) 634.
[34] E.B. Anderson, T.E. Long, Polymer, 51 (2010) 2447.
Applied Chemistry Today
Volume 13, Issue 47
June 2018
Pages 9-20

Files

Share

How to cite

Statistics