Controlled drug release is one method for Stabilization of the drug concentration and its gradually releasing during the period of cure to make the most desire cure effect with decreasing the drug dose consumption. The application of polymers has been extended in this filed. This study includes the synthesis of p-styrene sulphonyl sulfametazine as monomer from p-styrene sulfonyl chlorid, and then the monomer is polymerized with AIBN (Azobis isobutyro nitrile) by free-radical polymerization mechanism, at the temperature 80 °C. The prepared products were characterized by 1H NMR and IR spectra. Then, the drug release ability of the polymer was test in buffer solution with PH = 1.4 at the temperature of 37°C. The results from the UV absorption of polymer established that, the polymer is able to release drug.
Amini Manesh, A., Khazaei, A., & Asgari, A. (2013). Control drug release delivery of new sulfametazine drugconjugated
poly p-styrene sulphonate system. Applied Chemistry Today, 8(29), 19-24. doi: 10.22075/chem.2013.2458
MLA
Abbas Amini Manesh; Ardeshir Khazaei; Asieh Asgari. "Control drug release delivery of new sulfametazine drugconjugated
poly p-styrene sulphonate system". Applied Chemistry Today, 8, 29, 2013, 19-24. doi: 10.22075/chem.2013.2458
HARVARD
Amini Manesh, A., Khazaei, A., Asgari, A. (2013). 'Control drug release delivery of new sulfametazine drugconjugated
poly p-styrene sulphonate system', Applied Chemistry Today, 8(29), pp. 19-24. doi: 10.22075/chem.2013.2458
VANCOUVER
Amini Manesh, A., Khazaei, A., Asgari, A. Control drug release delivery of new sulfametazine drugconjugated
poly p-styrene sulphonate system. Applied Chemistry Today, 2013; 8(29): 19-24. doi: 10.22075/chem.2013.2458
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