Synthesis, Characterization, Antibacterial properties and DNA Binding of a Th(IV) Complex

Document Type : Original Article

Authors

Department of Chemistry, University of Sistan and Baluchestan, Zahedan, Iran

Abstract

In this investigation, we have reported the synthesis of the complex [Th(5,5´-dmbpy)3](NO3)4](1) that 5,5´-dmbpy =5,5´-dimethyl-2,2´-bipyridine. This complex has been characterized using spectral methods (FT-IR, UV-Vis, 1H-NMR and luminescence), elemental analysis and the Cyclic Voltammetry (CV) method. The FT-IR data shows that 5,5´-dimethyl-2,2´-bipyridine (5, 5´- dmbpy) ligand adduct to metal centers by nitrogen atoms. Electronic spectra of (1) shows ligand field transitions and charge transfer (CT) bands. Electrochemical data for the complex in the DMF solution show reduction and oxidation processes for the Thorium ion and ligand. The interactions of complex (1) with FS-DNA have been investigated using UV–Vis and gel electrophoresis. The binding constant (Kb) was calculated using UV–Vis technique (Kb=3.5×105). Also, DNA cleavage was studied using agarose gel electrophoresis. The antibacterial properties and fluorescence property of complex (1) have also been examined. The in vitro biological screening effects of the complex and ligand were tested against different types of bacterium and [Th(5,5´-dmbpy)3](NO3)4](1) shows antibacterial properties.

Keywords

Main Subjects

References

[1] R.K. Saha, T.I. Khan, Surf. Coat. Technol., 205 (2010) 890.
[2] M. Sabri, A.A. Sarabi, S.M. Naseri Kondelo, Mater. Chem. Phys., 136 (2012) 566.
[3] A. Cziraki, B. Fogaassy, I. Geroces, E. Toth-Kadar, I. Bakonyi, J. Mater. Sci., 29 (1994) 4771.
[4] A. Cziraki, Z. Tonkovics, I. Geroces, B. Fogarassy, I. Groma, E. Toth-Kadar, T. Tarnoczi, I. Bakonyi, Mater. Sci. Eng. A, 179-180 (1994) 531.
[5] I. Bakonyi, E. Toth-Kadar, T. Tarnoczi, L.K. Varga, A. Cziraki, I. Geroces, B. Fogarassy, Nanostruct. Mater. 3 (1993) 155.
[6] S .Lauer, Z. Guan, H .Wolf, H. Natter, M .Schmelzer, R. Hempelmann, Nanostruct. Mater. 12 (1999) 955.
[7] M.J. Aus, B .Szpunar, A.M. El-Sherik, U. Erb, G. Palumbo, K.T. Aust , Scr. Metall. Mater., 27 (1992) 1639.
[8] H. Wolf, Z. Guan, X. Li, T. Wichert, Hyperfine Interact.136 (2001) 281.
[9] F. Nasirpouri, M.R. Sanaeian, A.S. Samardak, E.V. Sukovatitsina, A.V. Ognev, L.A. Chebotkevich, M.G. Hosseini, M. Abdolmaleki, Appl. Surf. Sci, 292 (2014) 795.
[10] S.L. Kuo, Y.C. Chen, M.D. Ger, W.H. Hwu, Mater. Chem. Phys., 86 (2004) 5.
[11] M. Ger, Mater. Chem. Phys., 87 (2004) 67.
[12] L. Chen, L. Wang, Z. Zeng, J. Zhang, Mater. Sci. Eng. A, 434 (2006) 319-325.
[13] M. Wang, J. Appl. Electrochem., 38 (2008) 245.
[14] A.A. Amadeh, Int. J. Mod. Phys. B, 22 (2008) 3037.
[15] C. Guo, Y. Zuo, X. Zhao, J. Zhao, J. Xiong, Surf. Coat. Technol., 202 (2008) 3385.
[16] E. Pompei, L. Magagnin, N. Lecis, P.L. Cavallotti, Electrochim. Acta, 54 (2009) 2571.
[17] H. Gul, F. Kilic, S. Aslan, A. Alp, H. Akbulut, Wear, 267 (2009) 976.
[18] M.G. Hosseini, E. Ariankhah, Journal of Applied Chemistry, 11 (2017) 147.
Applied Chemistry Today
Volume 13, Issue 49
December 2018
Pages 29-36

Files

Share

How to cite

Statistics