In this work, an electrochemical sensor based on carbon paste electrode modified with Au nanoparticle and 1-methyl-3-octylimidazolium chloride was fabricated as a sensor for determination of methyldopa. Au nanoparticle synthesized by Nettle extract and characterized by UV-Vis and TEM methods. The modified electrode showed good electrical conductivity for methyldopa signal. The effect of pH showed that electro-oxidation of methyldopa occurred with two electrons and two protons. The fabricated sensor showed the dynamic range 0.08-550 μM with detection limit 0.04 μM for determination of methyldopa. In the final step, the fabricated sensor was used successfully for determination of methyldopa in tablet and urine samples.
Abbasghorbani, M. (2019). Design of sensitive electrochemical sensor as the analytical tool for methyldopa in drug and biological samples. Applied Chemistry Today, 14(52), 77-86. doi: 10.22075/chem.2019.15076.1455
MLA
Maryam Abbasghorbani. "Design of sensitive electrochemical sensor as the analytical tool for methyldopa in drug and biological samples", Applied Chemistry Today, 14, 52, 2019, 77-86. doi: 10.22075/chem.2019.15076.1455
HARVARD
Abbasghorbani, M. (2019). 'Design of sensitive electrochemical sensor as the analytical tool for methyldopa in drug and biological samples', Applied Chemistry Today, 14(52), pp. 77-86. doi: 10.22075/chem.2019.15076.1455
VANCOUVER
Abbasghorbani, M. Design of sensitive electrochemical sensor as the analytical tool for methyldopa in drug and biological samples. Applied Chemistry Today, 2019; 14(52): 77-86. doi: 10.22075/chem.2019.15076.1455
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