Synthesis and characterization of ZnS/CuFe2O4 Magnetic hybrid nanocatalyst and its application in the synthesis of 2-amino-3-cyano-4H-pyran derivatives

Document Type : Original Article


Faculty of Chemistry, Iran University of Science and Technology, Tehran, Iran


The ZnS/CuFe2O4 magnetic hybrid nanocatalyst was synthesized for the first time by a simple procedure. Investigation and characterization of this catalyst were carried out using energy-dispersive X-ray spectroscopy (EDX), field emission scanning electron microscopy (FESEM), X-ray diffraction (XRD) and vibrating sample magnetometer (VSM) analyses. Synthetic nanoparticles were used as a magnetic and heterogeneous catalyst for the one-pot synthesis of 2-amino-3-cyano-4H-pyran derivatives with condensation of dimedone, aromatic aldehydes and malononitrile in ethanol at room temperature. The reported method has advantages such as mild conditions, good yields, simple separation of products from the reaction mixture and the use of biocompatible solvent and inexpensive catalyst. Nanocatalyst ZnS/CuFe2O4 was easily separated from the reaction using an external magnetic field and reused several times in reactions without appreciable reduction in catalytic activity.


[1] R. Bavandpour, H. Karimi-Maleh, M. Asif, V.K. Gupta, N. Atar, M. Abbasghorbani, J. Mol. Liq., 213 (2016) 369.
[2] A.S. Kumar, M.A. Reddy, M. Knorn, O. Reiser, B. Sreedhar,        Eur. J. Org. Chem., 2013 (2013) 4674.
[3] M. El-Remaily, A. Manaf-Ali, A. Abu-dief,  Tetrahedron, 71 (2015) 2579.
[4] H. Hou, G. Xu, S. Tan, Y. Zhu, Infrared Phys. Technol., 85 (2017) 261.
[5] A.V. Nakhate, G.D. Yadav, ChemistrySelect, 2 (2017) 2395.
[6] P. Paramasivan, P. Venkatesh, PHYSICA E., 84 (2016) 258.
[7] K.M. Yeo, J. Shin, I.S. Lee,  Chem. Commun., 46 (2010) 64.
[8] A. Mehdi, A. Ali, J. Of Applied Chemistry, 48 (1397) 285, in Persian.
[9] Y.B. Wagh, Y.A. Tayade, S.A. Padvi, B.S. Patil, N.B. Patil, D.S. Dalal, Chin. Chem. Lett. 26 (2015) 1273.
[10] SH. Tayebeh, A. Ali, T, Elham, J. Of Applied Chemistry, 43 (1396) 255, in Persian.
[11] M.G. Dekamin, S.Z. Peyman, Z. Karimi, S. Javanshir, M.R. Naimi-Jamal, M. Barikani, Int. J. Biol. Macromol., 87 (2016) 172.
[12] B. Maleki, S. Sheikh, Org. Prep. Proced. Int., 47 (2015) 368.
[13] D.D. Pham, G. Vo-Thanh, T.N. Le, Synth. Commun., 47 (2017) 1684.
[14] A. Molla, S. Hussain, RSC Adv., 6 (2016) 5491.
[15] I. Kharbangar, M.R. Rohman, H. Mecadon, B. Myrboh, Int. J. Org. Chem., 2 (2012) 5.
[16] H. Ramadoss, H. Kiyani, S.S. Mansoor, Iran. J. Chem. Chem. Eng., 36 (2017) 19.
[17] A. Maleki, R. Ghalavand, R. Firouzi Haji, Appl. Organomet. Chem., 32 (2018) e3916.
[18] T. Shamsi, A. Amoozadeh, S.M. Sajjadi, E. Tabrizian, Appl. Organomet. Chem. , 31 (2017) e3636.
[19] S.F. Hojati, A. Amiri, N. MoeiniEghbali, S. Mohamadi, Appl. Organomet. Chem., 32 (2018) e4235.
[20] L. Chen, J. Lin, B. Chen, L. Zhao, Res. Chem. Intermediat., 43 (2017) 6691.
[21] H. Naeimi, M.F. Zarabi, Res. Chem. Intermediat., 44 (2018) 3227.
[22] K. Niknam, N. Borazjani, R. Rashidian, A. Jamali, Chinese J. Catal., 34 (2013) 2245.
[23] S. Nemouchi, R. Boulcina, B. Carboni, A. Debache, C. R. Chim., 15 (2012) 394.
[24] B. Maleki, H. Eshghi, M. Barghamadi, N. Nasiri, A. Khojastehnezhad, S. Sedigh Ashrafi, O. Pourshiani, Res. Chem. Intermediat., 42 (2016) 3071.
[25] M. Behrooz, A. J. Sedigheh, B. Mehdi, R. A. Hosseinasghar, V. Hojat, J. Of Applied Chemistry, 48 (1397) 209, in Persian.
[26] R. Heydari, R. Shahraki, M. Hossaini, A. Mansouri, Res. Chem. Intermediat., 43 (2017) 4611.
[27] S.S. Katkar, M.K. Lande, B.R. Arbad, S.T. Gaikwad, Chin. J. Chem. Phys., 29 (2011) 199.
[28] P. Sharma, M. Gupta, R. Kant, V.K. Gupta, RSC Adv., 6 (2016) 32052.