We have developed a convenient and efficient method for coupling of aryl iodides and bromides with terminal alkynes. The protocol uses CuI as catalyst, 1, 10-phenanthroline as ligand, KF/Al2O3 as base and toluene as solvent. The method is suitable for the synthesis of functionalized aryl-alkynes.
Hosseinzadeh, R., Mohadjerani, M., & Tavakoli, R. (2009). Efficient Sonogashira Coupling Reaction Catalyzed by Copper (I) Iodide in the Presence of KF/Al2O3. Applied Chemistry Today, 4(10), 3-8. doi: 10.22075/chem.2017.544
MLA
Rahman Hosseinzadeh; Maryam Mohadjerani; Rahmatollah Tavakoli. "Efficient Sonogashira Coupling Reaction Catalyzed by Copper (I) Iodide in the Presence of KF/Al2O3", Applied Chemistry Today, 4, 10, 2009, 3-8. doi: 10.22075/chem.2017.544
HARVARD
Hosseinzadeh, R., Mohadjerani, M., Tavakoli, R. (2009). 'Efficient Sonogashira Coupling Reaction Catalyzed by Copper (I) Iodide in the Presence of KF/Al2O3', Applied Chemistry Today, 4(10), pp. 3-8. doi: 10.22075/chem.2017.544
VANCOUVER
Hosseinzadeh, R., Mohadjerani, M., Tavakoli, R. Efficient Sonogashira Coupling Reaction Catalyzed by Copper (I) Iodide in the Presence of KF/Al2O3. Applied Chemistry Today, 2009; 4(10): 3-8. doi: 10.22075/chem.2017.544