p-Toluenesulfonyl Chloride (p-TsCl) as a New and Effective Catalyst for Acetylation and Formylation of Hydroxyl Compounds under Mild Conditions

Rostamia, Amin; Mantashlob, Fatemeh; Khazaei, Ardeshir

doi:10.22075/chem.2017.547

p-Toluenesulfonyl Chloride (p-TsCl) as a New and Effective Catalyst for Acetylation and Formylation of Hydroxyl Compounds under Mild Conditions

Authors

amin Rostamia

fatemeh Mantashlob

ardeshir Khazaei

10.22075/chem.2017.547

Abstract

The first catalytic application of p-TsCl for efficient acetylation of various types of alcohols and phenols with acetic anhydride in both solution and solvent-free conditions is reported. Also structurally diverse alcohols were formylated using formic acid based on the use of catalytic amount of p-TsCl under solvent-free condition. The reactions were carried out in short reaction time and in good to excellent yields at room temperature.

Keywords

p-Toluenesulfonyl Chloride

Hydroxyl compounds

Acetylation

Formylation