Theoretical Studies of Using Amino Acids as a New Class of Antidote Drugs and their Possible Complexes with Zn2+as Antidote Drugs.

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Abstract

This paper introduces a new class of bidentate ligands as antidote drugs. By semi-empirical AM1 method calculations, we showed that natural amino acids could be used as theoretically good antidote drugs. To reach this goal, we have calculated the stability energies of glycine, alanine, valine, leucine, isoleucine, serine and threonine and their complexes with Zn2+ as indicated.

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Applied Chemistry Today
Volume 4, Issue 10
June 2009
Pages 57-62

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