Voltammetric determination of acetaminophen by using carbon paste electrode modified by hierarchically structured cobalt



In this approach, hierarchically structured cobalthas been applied as modifier for determination of acetaminophen. These nanostructures have been synthesized using a chemical reduction method. They were characterized by scanning electron microscopy and cyclic voltammetry. The modified electrode exhibits an electrocatalytic activity toward oxidation of acetaminophen. The effect of pH and scan rate has been studied. Differential pulse voltammetry has been used for quantitative determination af acetaminophen. A dynamic linear range 1×10-3Mto 1×10-6M with a limit of detection 5× 10-7 M obtained. The modified electrode has been successfully applied for determination of acetaminophen in synthetic serum and commercial tablets.