Applied Chemistry Today

Applied Chemistry Today

Simultaneous Determination of Ascorbic Acid, Dopamine, and Uric Acid by Differential Pulse Voltammetry Using Poly(Chromazurol s) Modified Glassy Carbon Electrode

Authors
Masoumeh Taei
Abouzar Sharifzadeh
Fouladgar Masoud
Foroozan Hasanpour
10.22075/chem.2017.628
Abstract
The Chromazurol s has been electropolymerized on the glassy carbon electrode and the Poly- Chromazurol s modified glassy carbon electrode (PCSMGCE) has shown excellent electrocatalytic activity toward the oxidation of ascorbic acid in phosphate buffer solution (pH=3). It was used for the simultaneous determination of ascorbic acid (AA), dopamine (DA), and uric acid (UA). Analytical parameters were optimized and electrochemical behavior of modified electrode was studied. The calibration curves were obtained over the range of 3.0-2200.0 µmol L–1 AA, 0.09-980.0 µmol L–1 DA, and 0.05-900.0 µmol L–1 UA. Detection limits of 1.7 µmol L–1 AA, 0.05 µmol L–1 DA, and 0.03 µmol L–1 UA were obtained at pH 3.0. Prepared modified electrode had satisfactory results for determination of DA, AA and UA in dopamine injection solution, vitamin C tablets and human urine samples.
Keywords
Poly(Chromazurol s)
Glassy carbon electrode
Ascorbic acid
Dopamine
Uric acid
Differential pulse voltammetry
Applied Chemistry Today
Volume 7, Issue 25
Autumn 2012
Pages 59-67