A simple and efficient method has been presented for the synthesis of 3,4,5-substituted furan-2-one derivatives. One-pot three-component reaction of aromatic amines, aromatic aldehydes and dialkyl acetylenedicarboxylates in the presence of oxalic acid dihydrate in ethanol as a green solvent leads to furan-2-one dreviatives. Some of the advantages of this procedure are mild conditions, high atom economy inexpensive catalyst and high yields. Moreover, the products were obtained through simple filtering and no need to column chromatography.
(2016). One-pot three-component synthesis of substituted furan-2-one derivatives using oxalic acid dihydrate as a catalyst. Applied Chemistry Today, 11(40), 99-106. doi: 10.22075/chem.2017.759
MLA
. "One-pot three-component synthesis of substituted furan-2-one derivatives using oxalic acid dihydrate as a catalyst", Applied Chemistry Today, 11, 40, 2016, 99-106. doi: 10.22075/chem.2017.759
HARVARD
(2016). 'One-pot three-component synthesis of substituted furan-2-one derivatives using oxalic acid dihydrate as a catalyst', Applied Chemistry Today, 11(40), pp. 99-106. doi: 10.22075/chem.2017.759
VANCOUVER
One-pot three-component synthesis of substituted furan-2-one derivatives using oxalic acid dihydrate as a catalyst. Applied Chemistry Today, 2016; 11(40): 99-106. doi: 10.22075/chem.2017.759
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