Application of tin oxide- inverse spinel zinc stannate nanocomposite modified carbon paste electrode for the voltammetric determination of pyridium in pharmaceutical and biological samples

Document Type : Original Article



The SnO2-Zn2SnO4 nanocomposite was successfully prepared via a simple solid state method. The resulted nanocomposite was characterized by field emission scanning electron microscopy (FE-SEM), X-ray diffraction (XRD) and Fourier transform infrared spectroscopy (FT-IR). Then, a novel pyridium sensor has been developed based on SnO2-Zn2SnO4 nanocomposites modified carbon paste electrode (SnO2-Zn2SnO4/CPE).   The fabricated sensor exhibits outstanding electrocatalytic activities toward the oxidation of pyridium. The  oxidation  peak  current  was  proportional  to the  concentration  of  pyridium  from  0.3  to   607.0  µM with  a detection  limit  of   0.009  µM  at signal to noise ratio of 3. The proposed method was examined as a selective, simple and precise method for voltammetric determination of pyridium in real samples with satisfactory results.


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