نوع مقاله : مقاله علمی پژوهشی
نویسندگان
1 دانشکده شیمی، گروه شیمی تجزیه، دانشگاه دامغان، دامغان، ایران
2 دانشکده علوم محیطی، دانشگاه علوم و الکترونیک چین، چنگدو، چین
چکیده
کلیدواژهها
موضوعات
عنوان مقاله [English]
نویسندگان [English]
In this research work, NiO/carbon nanotube nanocomposite (NiO/CNTs) was synthesized using direct deposition method and characterized using Transmission electron microscopy (TEM) and elemental analysis (EDS). Then, carbon paste electrode modified with NiO/CNTs nanocomposite with optimal weight percentage (10% w/w) was prepared and the designed sensor was used to investigate the electrochemical behavior of epirubicin. The results showed that the highest sensitivity was achieved under neutral conditions. The designed sensor detected epirubicin well in the concentration range of 0.01-320 μM and a detection limit of 8 nM was obtained for the measurement of epirubicin on the surface of the new sensor. The modified sensor has shown good catalytic ability in increasing the oxidation current as well as reducing the drug overvoltage. Finally, the proposed sensor was used to measure epirubicin in injection and dextrose saline samples and the results showed a recovery percentage of 97.4%-102.8%, which is acceptable for a new sensor.
کلیدواژهها [English]
)