شیمى کاربردى روز

شیمى کاربردى روز

سنتز بهینه چارچوب‌ ایمیدازولات زئولیتی-67 و استفاده از آن به عنوان نانوزیم مقلد پراکسیداز برای سنجش رنگ سنجی هیدروژن پراکسید

نوع مقاله : مقاله علمی پژوهشی

نویسندگان
گروه شیمی معدنی، دانشکده شیمی ، دانشگاه گیلان، رشت، ایران
چکیده
در سال‌های اخیر، نانوساختارهایی با فعالیت شبه آنزیمی، به‌ویژه آنزیم‌های مقلد پراکسیداز، به عنوان جایگزین‌های امیدوارکننده ای برای آنزیم‌های طبیعی، در کاربردهای مختلفی مورد توجه قرار گرفته‌اند. در این مطالعه، چارچوب ایمیدازولات زئولیتی-67 (ZIF-67) مبتنی بر کبالت با راندمان بالا، از طریق قراردادن محلول اتانولی واکنش‌دهنده‌ها در جو آمونیاک و در دمای محیط سنتز شد. ZIF-67 به دست آمده فعالیت شبه پراکسیدازی کارآمدی را نشان داد. مطالعات سینتیکی نشان داد که ZIF-67 سنتز شده میل اتصال قوی تری به اورتوفنیلن دی آمین (OPD)، به عنوان سوبسترا و همچنین سرعت واکنش بالاتری نسبت به آنزیم پراکسیداز ترب کوهی (HRP) دارد. یک روش رنگ سنجی مبتنی بر ZIF-67 برای تشخیص H2O2 (ناحیه پاسخ خطی M 4-10 × 96/9 − 4-10) توسعه داده شد. انتظار می رود این رویکرد سنتزی آسان و کم هزینه، تولید در مقیاس بزرگ و کاربرد عملی ZIF-67 و مشتقات آن را به عنوان آنزیم های مصنوعی در آینده تسهیل نماید.
کلیدواژه‌ها
موضوعات

عنوان مقاله English

Optimized Synthesis of Zeolitic Imidazolate Framework-67 and its Application as a Peroxidase-Mimicking Nanozyme for Colorimetric Detection of Hydrogen Peroxide

نویسندگان English

Zohre Ebrahimpour
Zeinab Moradi-Shoeili
Department of Inorganic Chemistry, Faculty of Chemistry, University of Guilan, Rasht, Iran
چکیده English

In recent years, nanostructures with enzyme-like activity, particularly peroxidase mimics, have been regarded as promising alternatives to natural enzymes in a variety of applications. In this study, a cobalt-based zeolitic imidazolate framework-67 ( ZIF - 67 ) was synthesized with high efficiency by exposing an aqueous solution of the reactants to an ammonia atmosphere at ambient temperature. The obtained ZIF- 67 exhibited efficient peroxidase-like activity. Kinetic studies demonstrated that the synthesized ZIF -67 had a stronger binding affinity to o-phenylenediamine ( OPD ) as a substrate, as well as higher reaction rates compared to the enzyme horseradish peroxidase ( HRP ). A ZIF-67-based colorimetric method was further developed for H2O2 detection ( linear response range, 10-4-9.96 × 10-4 M ). This facile and low cost synthesis approach is expected to facilitate the large-scale production and practical application of ZIF - 67 and its derivatives as artificial enzymes in the future.

کلیدواژه‌ها English

Zeolitic imidazolate framework
ZIF-67
Peroxidase-like activity
Kinetic study
Colorimetric sensor
[1] Kaushal, J., Singh, G. & Arya, S.K. (2022). Emerging trends and future prospective in enzyme technology. In Kuddus, M., Aguilar, C. N. (Eds.), Value-addition in food products and processing through enzyme technology (491–503). Academic Press.
[2] Sharma, A., Gupta, G., Ahmad, T., Mansoor, S. & Kaur, B., (2021). Enzyme engineering: current trends and future perspectives. Food Reviews International, 37(2), 121-154.
[3] He, J., Zhang, Y., Zhang, X., & Huang, Y. (2018). Highly efficient Fenton and enzyme-mimetic activities of NH2-MIL-88B (Fe) metal organic framework for methylene blue degradation. Scientific reports, 8(1), 1-8.
[4] Kuah, E., Toh, S., Yee, J., Ma, Q., & Gao, Z. (2016). Enzyme mimics: advances and applications. Chemistry–A European Journal22(25), 8404-8430.
[5] Hoarau, M., Hureau, C., Gras, E., & Faller, P. (2016). Coordination complexes and biomolecules: A wise wedding for catalysis upgrade. Coordination Chemistry Reviews308, 445-459.
[6] Shin, H. Y., Park, T. J., & Kim, M. I. (2015). Recent research trends and future prospects in nanozymes. Journal of Nanomaterials, 2015(1), 756278-756288.
[7] Gawande, M. B., Goswami, A., Felpin, F. X., Asefa, T., Huang, X., Silva, R., ... & Varma, R. S. (2016). Cu and Cu-based nanoparticles: synthesis and applications in catalysis. Chemical reviews116(6), 3722-3811.
[8] Wei, H & Wang, E. (2013). Nanomaterials with enzyme-like characteristics (nanozymes): next-generation artificial enzymes. Chemical Society Reviews42(14), 6060-6093.
[9] Wu, J., Li, S., & Wei, H. (2018). Integrated nanozymes: facile preparation and biomedical applications. Chemical Communications54(50), 6520-6530.
[10] Xie, J., Zhang, X., Wang, H., Zheng, H., & Huang, Y. (2012). Analytical and environmental applications of nanoparticles as enzyme mimetics. Trends in Analytical Chemistry39, 114-129.  
[11] Gawande, M. B., Goswami, A., Felpin, F. X., Asefa, T., Huang, X., Silva, R., ... & Varma, R. S. (2016). Cu and Cu-based nanoparticles: synthesis and applications in catalysis. Chemical reviews116(6), 3722-3811.  
[12] Kim, M. Y., & Kim, J. (2017). Chitosan microgels embedded with catalase nanozyme-loaded mesocellular silica foam for glucose-responsive drug delivery. ACS Biomaterials Science & Engineering3(4), 572-578.
[13] Champe, P. C., Harvey, R. A., & Ferrier, D. R. (2005). Biochemistry. Lippincott Williams & Wilkins.
[14] Sellami, K., Couvert, A., Nasrallah, N., Maachi, R., Abouseoud, M. & Amrane, A., (2022). Peroxidase enzymes as green catalysts for bioremediation and biotechnological applications: A review. Science of the Total Environment, 806, 150500.
[15] Peng, Y., Wang, Z., Liu, W., Zhang, H., Zuo, W., Tang, H., ... & Wang, B. (2015). Size-and shape-dependent peroxidase-like catalytic activity of MnFe 2O4 nanoparticles and their applications in highly efficient colorimetric detection of target cancer cells. Dalton Transactions44(28), 12871-12877.
[16] Zhong, C., He, M., Lou, K., & Gao, F. (2017). The application, neurotoxicity, and related mechanism of silica nanoparticles. In Neurotoxicity of Nanomaterials and Nanomedicine. Academic Press.
[17] Gao, L., Zhuang, J., Nie, L., Zhang, J., Zhang, Y., Gu, N., Wang, T., Feng, J., Yang, D., Perrett, S. & Yan, X., (2007). Intrinsic peroxidase-like activity of ferromagnetic nanoparticles. Nature nanotechnology, 2(9), 577-583.
[18] Singh, S., Tripathi, P., Kumar, N., & Nara, S. (2017). Colorimetric sensing of malathion using palladium-gold bimetallic nanozyme. Biosensors and Bioelectronics92, 280-286.
[19] Manea, F., Houillon, F. B., Pasquato, L., & Scrimin, P. (2004). Nanozymes: Gold‐nanoparticle‐based transphosphorylation catalysts. Angewandte Chemie116(45), 6291-6295.
[20] Gao, L., Zhuang, J., Nie, L., Zhang, J., Zhang, Y., Gu, N., ... & Yan, X. (2007). Intrinsic peroxidase-like activity of ferromagnetic nanoparticles. Nature nanotechnology2(9), 577-583.
[21] Luo, W., Li, Y. S., Yuan, J., Zhu, L., Liu, Z., Tang, H., & Liu, S. (2010). Ultrasensitive fluorometric determination of hydrogen peroxide and glucose by using multiferroic BiFeO3 nanoparticles as a catalyst. Talanta81(3), 901-907.
[22] Lin, T., Zhong, L., Guo, L., Fu, F., & Chen, G. (2014). Seeing diabetes: visual detection of glucose based on the intrinsic peroxidase-like activity of MoS2 nanosheets. Nanoscale6(20), 11856-11862.
[23] Dai, Z., Liu, S., Bao, J., & Ju, H. (2009). Nanostructured FeS as a mimic peroxidase for biocatalysis and biosensing. Chemistry–A European Journal15(17), 4321-4326.
[24] Song, Y., Qu, K., Zhao, C., Ren, J., & Qu, X. (2010). Graphene oxide: intrinsic peroxidase catalytic activity and its application to glucose detection. Advanced Materials22(19), 2206-2210.
[25] Zhao, R., Zhao, X., & Gao, X. (2015). Molecular-level insights into intrinsic peroxidase-like activity of nanocarbon oxides. Chemistry: A European Journal21, 960-964.
 [26] Freund, R., Zaremba, O., Arnauts, G., Ameloot, R., Skorupskii, G., Dincă, M., Bavykina, A., Gascon, J., Ejsmont, A., Goscianska, J. & Kalmutzki, M., (2021). The current status of MOF and COF applications. Angewandte Chemie International Edition, 60(45), 23975-24001.
[27] Nikseresht, A., Shokri, N., Mohammadi, M., Afzalinia, A., Nosratollahi, S. & Rostamizadeh, S., (2024). TMU-16-NH2: A metal–organic framework as an efficient, green, and heterogeneous catalyst for the Michael addition annulations for the synthesis of a new series of 2, 4-Diphenylpyrido [4, 3-d] pyrimidines. Polycyclic Aromatic Compounds, 44(6), 3771-3786.41.
[28] Nikseresht, A., Ghoochi, F. & Mohammadi, M., (2024). Postsynthetic modification of amine-functionalized MIL-101 (cr) metal–organic frameworks with an EDTA–Zn (II) complex as an effective heterogeneous catalyst for Hantzsch synthesis of polyhydroquinolines. ACS omega, 9(26), 28114-28128.
[29] Nikseresht, A., Mehravar, R. & Mohammadi, M., (2024). RSM optimization of Friedel–Crafts C-acylation of para-fluorophenol over the catalysis of phosphomolybdic acid encapsulated in MIL-53 (Fe) metal organic frameworks. Nanoscale Advances, 6(12), 3158-3168.
[30] Piroozi, S., Tanhaei, B., Ayati, A., Niknam Shahrak, ., & Saei Moghadam, M. (2022). Investigation of photo catalytic properties of ZIF-8 emitted based on titanium dioxide nano tubes in removal of aqueous pollutants, Applied Chemistry Today, 17(62), 99-114. (in persion)
[31] Jacobs, P. A., Flanigen, E. M., Jansen, J. C., & van Bekkum, H. (2001). Introduction to zeolite science and practice. Elsevier.
[32] Azadi, S., Zare-Dorabei, R., Hamidi, F., & Safarifard, V. (2020). Synthesis of GQD@ZIF-8 nano hybrids and its application as a lead optical sensor, Applied Chemistry Today, 15(55), 327-342. (in persion)
[33] FurukawaH,Y. (2009). Storage of hydrogen, meth aneandcarbondioxidein highly porous covalentorganic frameworks for clean energy applications. Journal of the American Chemical Society131(25), 8875-8883.
[34] Dhakshinamoorthy, A., Alvaro, M., Hwang, Y. K., Seo, Y. K., Corma, A., & Garcia, H. (2011). Intracrystalline diffusion in Metal Organic Framework during heterogeneous catalysis: Influence of particle size on the activity of MIL-100 (Fe) for oxidation reactions. Dalton Transactions40(40), 10719-10724.
[35] Maruyama, W., Dostert, P., Matsubara, K., & Naoi, M. (1995). N-methyl (R) salsolinol produces hydroxyl radicals: involvement to neurotoxicity. Free Radical Biology and Medicine19(1), 67-75.
[36] Hu, A. L., Liu, Y. H., Deng, H. H., Hong, G. L., Liu, A. L., Lin, X. H., ... & Chen, W. (2014). Fluorescent hydrogen peroxide sensor based on cupric oxide nanoparticles and its application for glucose and l-lactate detection. Biosensors and Bioelectronics61, 374-378.
[37] Niu, X., Lan, M., Zhao, H., & Chen, C. (2013). Highly sensitive and selective nonenzymatic detection of glucose using three-dimensional porous nickel nanostructures. Analytical chemistry, 85(7), 3561-3569.
[38] Deng, X., Fang, Y., Lin, S., Cheng, Q., Liu, Q., & Zhang, X. (2017). Porphyrin-based porous organic frameworks as a biomimetic catalyst for highly efficient colorimetric immunoassay. ACS applied materials & interfaces9(4), 3514-3523.
[39] Lu, J., Zhang, H., Li, S., Guo, S., Shen, L., Zhou, T., ... & Zhang, Y. (2020). Oxygen-vacancy-enhanced peroxidase-like activity of reduced Co3O4 nanocomposites for the colorimetric detection of H2O2 and glucose. Inorganic chemistry59(5), 3152-3159.
[40] Ebrahimi, A., & Mansournia, M. (2017). Cost-effective fabrication of thermal-and chemical-stable ZIF-9 nanocrystals at ammonia atmosphere. Journal of Physics and Chemistry of Solids111, 12-17.
[41] Aumiller Jr, W.M., Davis, B.W., Hatzakis, E. & Keating, C.D. (2014). Interactions of macromolecular crowding agents and cosolutes with small-molecule substrates: effect on horseradish peroxidase activity with two different substrates. The Journal of Physical Chemistry B, 118(36), 10624-10632.
[42] Qin, J., Wang, S. & Wang, X., 2017. Visible-light reduction CO2 with dodecahedral zeolitic imidazolate framework ZIF-67 as an efficient co-catalyst. Applied Catalysis B: Environmental, 209, 476-482.
[43] Farid, S., Qiu, W., Zhao, J., Song, X., Mao, Q., Ren, S. & Hao, C., 2020. Improved OER performance of Co3O4/N-CNTs derived from newly designed ZIF-67/PPy NTs composite. Journal of Electroanalytical Chemistry, 858, 113768-113778.
[44] Zhou, K., Mousavi, B., Luo, Z., Phatanasri, S., Chaemchuen, S. & Verpoort, F., 2017. Characterization and properties of Zn/Co zeolitic imidazolate frameworks vs. ZIF-8 and ZIF-67. Journal of Materials Chemistry A, 5(3), 952-957.
[45] Samoshina, N.M. & Samoshin, V.V., 2005. The Michaelis constants ratio for two substrates with a series of fungal (mould and yeast) β-galactosidases. Enzyme and microbial technology, 36(2-3), 239-251.
[46] Vetr, F., Moradi‐Shoeili, Z., & Özkar, S. (2018). Oxidation of o‐phenylenediamine to 2, 3‐
diaminophenazine in the presence of cubic ferrites MFe2O4 (M= Mn, Co, Ni, Zn) and the application in colorimetric detection of H2O2. Applied Organometallic Chemistry, 32(9), 4465-4474.
[47] Jia, H., Yang, D., Han, X., Cai, J., Liu, H., & He, W. (2016). Peroxidase-like activity of the Co3O4 nanoparticles used for biodetection and evaluation of antioxidant behavior. Nanoscale, 8(11), 5938-5945.
[48] Dong, J., Song, L., Yin, J. J., He, W., Wu, Y., Gu, N., & Zhang, Y. (2014). Co3O4 nanoparticles with multi-enzyme activities and their application in immunohistochemical assay. ACS applied materials & interfaces, 6(3), 1959-1970.
[46] Huang, W., Lin, T., Cao, Y., Lai, X., Peng, J., & Tu, J. (2017). Hierarchical NiCo2O4 hollow sphere as a peroxidase mimetic for colorimetric detection of H2O2 and glucose. Sensors, 17(1), 217.